Immunology

Unit – I: Overview of Immune system (15 Hrs.)

1. Immune system- Innate and adaptive immunity

2. Organs of Immune System- Primary Lymphoid Organs, Secondary Lymphoid Organs

3. Cells involved in immune response-Lymphoid Cells, B-lymphocytes, T-lymphocytes,

Natural Killer Cells, Mononuclear Phagocytes, Granulolytic Cells, Mast Cells, Dendritic

Cells

Unit – IV: T and B-Cell maturation, activation and differentiation (15 Hrs.)

1. T Cell maturation-Thymic selection of the t-cell repertoir

2. T -Cell Activation-TCR mediated signalling, effector and memory T cells

3. T cell differentiation- effector and memory T cells

4. B Cell maturation-Progenitor B cell proliferation

5. B -Cell Activation-signal drive in B cells

6. B cell differentiation-cellular events within germinal centers, induction