Historical perspectives, organization of lipids in micelles, liposomes. Components, properties and characterization of lipid bilayer.  Singer and Nicolson - fluid mosaic model.Assembly Of Biomembrane Biosynthesis and transport of phospholipids to plasma membrane and other organelle membranes. Role   of  transport  proteins  and  flippase.  Biosynthesis  of  membrane  proteins. Topology  of  membrane  proteins, Role  of  endoplasmic reticulum  -  post translational  modifications, core  glycosylation  and  targeting  of.  Targetting of proteins to plasma membrane, cell organelle and exoplasmic location, targetting signals and adaptor proteins.